Description

n-Acetyl 5-Bromo-2-Fluoroaniline is a high-purity, halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both bromine and fluorine substituents into complex molecules, facilitating fine-tuning of their physical, chemical, and biological properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance bioactivity and environmental stability.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its halogenated aromatic core.
• Chemical Biology & Proteomics: Acts as a versatile reagent for modifying peptides and proteins, or as a scaffold for developing molecular probes and enzyme inhibitors.
• Dye and Pigment Intermediate: Serves as a starting material for synthesizing complex halogenated dyes and pigments with specific color fastness and spectral properties.

Basic Information

Product Name	n-Acetyl 5-Bromo-2-Fluoroaniline
CAS No.	88288-12-4
Molecular Formula	C8H7BrFNO
Molecular Weight	232.05 g/mol
Synonyms	5-Bromo-2-fluoroacetanilide; N-(5-Bromo-2-fluorophenyl)acetamide; 1-Acetamido-5-bromo-2-fluorobenzene; Acetamide, N-(5-bromo-2-fluorophenyl)-; 2-Fluoro-5-bromoacetanilide; 5-Bromo-2-fluoro-N-acetylaniline; N-Acetyl-5-bromo-2-fluoroaniline
EINECS	Contact for details

Quality Control

Every batch of n-Acetyl 5-Bromo-2-Fluoroaniline is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.