Description

See Conotoxin M I is a highly specific and potent peptide neurotoxin derived from the venom of marine cone snails. This compound is of significant value in neuroscience and pharmaceutical research due to its selective antagonism of certain nicotinic acetylcholine receptors. It is primarily utilized by researchers in academic institutions, biotechnology firms, and pharmaceutical R&D departments for studying receptor function, pain pathways, and developing novel therapeutic leads.

Application

• Neuroscience Research: As a selective pharmacological tool for studying neuronal nicotinic acetylcholine receptor (nAChR) subtypes, particularly in signal transduction and synaptic physiology.
• Drug Discovery & Development: Serving as a lead compound or molecular template for the design of new analgesics and neuroprotective agents targeting specific receptor pathways.
• Biochemical Assays: Used in in vitro binding studies and functional assays to characterize receptor-ligand interactions and screen for potential modulators.
• Physiological Studies: Investigating the role of specific nAChR subtypes in pain perception, cognitive function, and neuromuscular junction activity.
• Toxin & Venom Research: A reference standard in comparative studies of conopeptides and marine natural products for their structure-activity relationships.

Basic Information

Product Name	See Conotoxin M I
CAS No.	88217-10-1
Molecular Formula	C95H146N34O27S5
Molecular Weight	~2293.8 g/mol
Synonyms	Conotoxin M I; Conotoxin MI; α-Conotoxin M I; α-Conotoxin MI; α-Conotoxin M I; SNX-325; ω-Conotoxin M I (historical); Mu-Conotoxin M I; Cone snail toxin M I; 88217-10-1
EINECS	Contact for details

Quality Control

Our See Conotoxin M I is produced and handled under stringent conditions to ensure batch-to-batch consistency and biological activity. Each lot is subjected to comprehensive analytical testing, including HPLC for purity verification, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) detailing purity, peptide content, and bioactivity data upon request, supporting compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. This product is hygroscopic (moisture-sensitive). Solutions should be prepared in appropriate buffers, aliquoted to avoid repeated freeze-thaw cycles, and stored at -80°C. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by AAA)
Molecular Weight	2293.8 ± 2 Da (by MS)
Solubility	Soluble in water or aqueous buffers
Biological Activity	Specified per batch (e.g., IC50)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.