Description

N,n-Dibenzyl-L-Serine Methyl Ester CAS NO 88099-67-6 is a protected derivative of the amino acid L-serine, featuring benzyl groups on the amine and a methyl ester on the carboxylate. This compound serves as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for peptide-based therapeutics.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected serine residue, where the dibenzyl and methyl ester groups prevent unwanted side reactions.
• Chemical Research: Employed in academic and industrial R&D laboratories for studying reaction mechanisms, developing new synthetic methodologies, and creating molecular libraries.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of complex organic molecules, including natural product analogs and specialty chemicals.
• Bioconjugation & Probe Development: Useful for the synthesis of labeled compounds and molecular probes used in biochemical assays and diagnostic research.

Basic Information

Product Name	N,n-Dibenzyl-L-Serine Methyl Ester
CAS No.	88099-67-6
Molecular Formula	C₁₈H₂₁NO₃
Molecular Weight	299.37 g/mol
Synonyms	L-Serine, N,N-dibenzyl-, methyl ester; Methyl N,N-dibenzyl-L-serinate; Methyl (2S)-2-(dibenzylamino)-3-hydroxypropanoate; (S)-Methyl 2-(dibenzylamino)-3-hydroxypropanoate; N,N-Dibenzylserine methyl ester; Dibenzyl-L-serine methyl ester; Serine, N,N-dibenzyl-, methyl ester, L-
EINECS	Contact for details

Quality Control

Our N,n-Dibenzyl-L-Serine Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements of research and pre-clinical development. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D = Specific value provided on COA
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.