Description

Pilsicainide is a class Ic antiarrhythmic agent, a sodium channel blocker specifically developed for the treatment of cardiac arrhythmias. Its high selectivity and unique electrophysiological profile make it a critical active pharmaceutical ingredient (API) for developing specialized cardiovascular medications. This compound is essential for pharmaceutical manufacturers and research institutions focused on cardiology, drug discovery, and the formulation of antiarrhythmic therapies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of antiarrhythmic drugs for treating ventricular and supraventricular arrhythmias.
• Cardiovascular Research: A key reference standard and tool compound in electrophysiological studies and pharmacological research on sodium channel function.
• Drug Development: Serves as a lead compound or intermediate in the synthesis of novel antiarrhythmic agents and related chemical entities.
• Analytical Standard: Used as a high-purity certified reference material (CRM) in quality control laboratories for HPLC, LC-MS, and other analytical method development.
• Clinical Trial Material: Supplied as GMP-grade material for use in pre-clinical and clinical studies of new cardiovascular treatments.

Basic Information

Product Name	Pilsicainide
CAS No.	88069-67-4
Molecular Formula	C17H24N2O
Molecular Weight	272.39 g/mol
Synonyms	Pilsicainide Hydrochloride (common salt form); SUN 1165; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidineacetamide; (R)-N-(2,6-Dimethylphenyl)-1-methyl-2-piperidineacetamide; (R)-Pilsicainide; 1-Methyl-2-piperidineacetic acid 2,6-dimethylanilide
EINECS	Contact for details

Quality Control

Our Pilsicainide is manufactured and tested under a strict quality management system. We offer material suitable for research and development, with higher grades available to meet pharmaceutical (GMP) standards upon request. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, ensuring traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single unknown impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.