Description

Pilsicainide Hydrochloride is a high-purity pharmaceutical active ingredient (API) and research chemical. This compound is a class IC antiarrhythmic agent, valued for its specific sodium channel blocking activity in cardiac tissue. It is essential for pharmaceutical R&D, analytical reference standard preparation, and the manufacturing of specialized cardiovascular medications.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of antiarrhythmic drugs for the treatment of ventricular and supraventricular tachyarrhythmias.
• Research & Development: Critical compound for preclinical and clinical studies investigating cardiac electrophysiology and new therapeutic approaches for heart rhythm disorders.
• Analytical Reference Standard: Serves as a high-purity standard for quality control (QC) and assurance (QA) in pharmaceutical manufacturing, including HPLC, LC-MS, and NMR analysis.
• Biochemical Research: Used in vitro studies to investigate the mechanism of action of sodium channel blockers on isolated cardiac tissues and cell lines.
• Metabolite Synthesis: Acts as a starting material or intermediate for the synthesis of related metabolites or derivatives for pharmacological profiling.

Basic Information

Product Name	Pilsicainide Hydrochloride
CAS No.	88069-49-2
Molecular Formula	C17H24N2O • HCl
Molecular Weight	308.85 g/mol (Hydrochloride salt)
Synonyms	Pilsicainide HCl; SUN 1165; N-(2,6-Dimethylphenyl)-1-methyl-2-piperidineacetamide Hydrochloride; (R)-N-(2,6-Dimethylphenyl)-1-methyl-2-piperidineacetamide Hydrochloride; (R)-Pilsicainide Hydrochloride; SUN-1165; 1-Methyl-2-piperidineacetic acid 2,6-dimethylanilide hydrochloride
EINECS	Contact for details

Quality Control

Our Pilsicainide Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.