Description

Cefepime CAS NO 88040-23-7 is a fourth-generation, broad-spectrum cephalosporin antibiotic belonging to the β-lactam class. It is valued for its enhanced stability against β-lactamase enzymes and potent activity against a wide range of Gram-positive and Gram-negative bacteria, including Pseudomonas aeruginosa. This active pharmaceutical ingredient (API) is essential for the formulation of injectable antibiotic drugs used in hospital and clinical settings to treat serious infections such as pneumonia, bacteremia, and febrile neutropenia.

Application

• Pharmaceutical API: Primary use as the active ingredient in the manufacture of sterile injectable antibiotic formulations.
• Hospital Infection Treatment: Formulated into drugs for treating complicated intra-abdominal infections, urinary tract infections (UTIs), skin and skin structure infections, and pneumonia.
• Empirical Therapy: Used in broad-spectrum empirical antibiotic therapy for febrile neutropenia patients.
• Combination Therapies: May be used in combination with other antimicrobial agents for synergistic effects against multi-drug resistant organisms.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for treating bacterial infections in animals.
• Research & Development: Serves as a reference standard and key intermediate in pharmaceutical R&D for novel antibiotic development.

Basic Information

Product Name	Cefepime
CAS No.	88040-23-7
Molecular Formula	C19H24N6O5S2
Molecular Weight	480.56 g/mol
Synonyms	1-[[(6R,7R)-7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methylpyrrolidinium hydroxide inner salt; BMY-28142; Cefepime Dihydrochloride Monohydrate; Maxipime; Axepim; Cefepime Hydrochloride; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-(1-methylpyrrolidinio)methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Cefepime is manufactured under strict quality systems to ensure it meets the stringent requirements for pharmaceutical active ingredients. Quality is assured through comprehensive analytical testing, including HPLC for purity and related substances, identification by IR and NMR, and tests for residual solvents and heavy metals. We can supply material compliant with USP/EP/BP monograph standards. A detailed Certificate of Analysis (COA) is provided with each batch to guarantee identity, purity, and potency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	+40° to +48° (c=1 in water)
pH (1% aqueous solution)	3.5 - 5.5

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.