Description

2-[4-(Iodoacetamido)Phenyl]-6-Methylbenzothiazole is a specialized benzothiazole derivative functionalized with an iodoacetamido group, serving as a critical intermediate and research chemical. This compound matters for its role as a versatile building block in organic synthesis and as a potential precursor for fluorescent probes and bioconjugation reagents. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing novel diagnostic agents, biochemical tools, and advanced materials.

Application

• Bioconjugation & Protein Labeling: The reactive iodoacetamido group selectively targets thiol groups (cysteine residues) in proteins and peptides for site-specific labeling and cross-linking studies.
• Fluorescent Probe Synthesis: Acts as a key precursor for developing benzothiazole-based fluorescent dyes and sensors used in bioimaging and cellular analysis.
• Pharmaceutical Intermediate: Utilized in the research and development of novel therapeutic agents, particularly those targeting amyloid-related pathways or requiring specific molecular scaffolds.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, or other advanced materials where the benzothiazole core imparts desired electronic or optical properties.
• Biochemical Research Reagent: Serves as a tool compound in enzymology and molecular biology for studying protein function and interaction through covalent modification.

Basic Information

Item	Details
Product Name	2-[4-(Iodoacetamido)Phenyl]-6-Methylbenzothiazole
CAS No.	87992-62-9
Molecular Formula	C16H13IN2OS
Molecular Weight	408.26 g/mol
Synonyms	N-[4-(6-Methyl-2-benzothiazolyl)phenyl]iodoacetamide; 2-(4'-Iodoacetamidophenyl)-6-methylbenzothiazole; Iodoacetamide-PBS; IAA-PBT; 6-Methyl-2-[4-(iodoacetamido)phenyl]benzothiazole; N-(4-(6-Methylbenzo[d]thiazol-2-yl)phenyl)-2-iodoacetamide
EINECS	Contact for details

Quality Control

Our 2-[4-(Iodoacetamido)Phenyl]-6-Methylbenzothiazole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C to -10°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and degradation. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.