Description

[6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[(Formyloxy)Phenylacetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a key advanced pharmaceutical intermediate in the synthesis of cephalosporin antibiotics. This compound matters because it serves as a critical building block for developing potent, broad-spectrum antibacterial agents, ensuring high-purity inputs for final API manufacturing. It is essential for pharmaceutical R&D laboratories, fine chemical synthesis units, and manufacturers focused on producing next-generation β-lactam antibiotics to address evolving microbial resistance.

Application

• Pharmaceutical Intermediate: Primary use as a high-value precursor in the synthesis of advanced cephalosporin antibiotic Active Pharmaceutical Ingredients (APIs).
• Antibiotic Research & Development: Serves as a crucial scaffold for medicinal chemists developing new β-lactam compounds with improved efficacy and resistance profiles.
• Fine Chemical Synthesis: Used in multi-step organic synthesis processes requiring a protected, reactive penicillin/cephalosporin nucleus derivative.
• GMP Manufacturing: Integral component in cGMP-compliant production lines for regulated antibiotic formulations.
• Academic & Institutional Research: Employed in biochemical and pharmacological studies investigating bacterial cell wall synthesis inhibition mechanisms.

Basic Information

Product Name	[6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[(Formyloxy)Phenylacetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	87932-78-3
Molecular Formula	C22H21N3O8S
Molecular Weight	487.48 g/mol
Synonyms	7-ADCA Formyloxy Phenylacetyl Derivative; 7-[(Formyloxy)phenylacetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporanic Acid Derivative; 7-FPAC; (6R,7R)-7-[(R)-2-(Formyloxy)-2-phenylacetamido]-3-(acetoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Advanced Cephalosporin Intermediate; β-Lactam Intermediate
EINECS	Contact for details

Quality Control

Our [6R-[6Alpha,7Beta(R*)]]-3-(Acetoxymethyl)-7-[(Formyloxy)Phenylacetamido]-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.