Description

Flufenamic Acid Glucuronide is a key metabolite of the non-steroidal anti-inflammatory drug (NSAID) flufenamic acid. This compound is of significant value in pharmaceutical research and development, particularly for studying drug metabolism, pharmacokinetics, and excretion pathways. It serves as a critical reference standard and analytical tool for scientists and quality control professionals in the pharmaceutical, contract research organization (CRO), and academic sectors.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the quantitative and qualitative analysis of flufenamic acid and its metabolites in biological matrices.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Essential for investigating the metabolic fate, bioavailability, and clearance mechanisms of flufenamic acid in preclinical and clinical research.
• Bioanalytical Method Development: Used to develop, validate, and calibrate analytical methods such as LC-MS/MS, HPLC-UV, and HPLC-FLD for accurate metabolite detection.
• Toxicology and Safety Assessment: Employed in studies to understand the safety profile and potential toxicological implications of flufenamic acid metabolites.
• Impurity Profiling and Characterization: Acts as a known impurity or degradation product standard for the quality control of flufenamic acid active pharmaceutical ingredient (API) and finished dosage forms.
• Academic and Institutional Research: Supports fundamental research in medicinal chemistry, pharmacology, and analytical chemistry within universities and research institutes.

Basic Information

Product Name	Flufenamic Acid Glucuronide
CAS No.	87816-74-8
Molecular Formula	C23H22F3NO8
Molecular Weight	497.42 g/mol
Synonyms	Flufenamic Acid β-D-Glucuronide; 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid β-D-Glucopyranosiduronic acid; N-(3-Trifluoromethylphenyl)anthranilic acid glucuronide; Flufenamic Acid Glucuronide Metabolite; Flufenamic Acid O-Glucuronide; Flufenamic Acid Glucuronide Standard; Flufenamic Acid Glucuronide (major metabolite)
EINECS	Contact for details

Quality Control

Our Flufenamic Acid Glucuronide is manufactured and handled under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and reference materials. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and chromatographic data (e.g., HPLC purity) is provided with every shipment to guarantee traceability and support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (typically 15-25°C) or as specified on the label or COA. For long-term storage, desiccate at -20°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.