Description

Ioversol is a non-ionic, low-osmolar, iodinated contrast medium belonging to the triiodinated benzene derivative class. It is a critical diagnostic agent used in medical imaging procedures to enhance the visibility of vascular structures and internal organs. This compound is essential for healthcare providers and pharmaceutical manufacturers specializing in diagnostic imaging solutions. Its primary value lies in providing clear radiographic contrast with a favorable safety profile for patient administration.

Application

• X-ray Contrast Media: The primary and most significant application is as an active pharmaceutical ingredient (API) in injectable formulations for radiographic procedures.
• Computed Tomography (CT Scan): Used for contrast-enhanced CT imaging of various anatomical regions, including the brain, spine, and body cavities.
• Angiography and Arteriography: Critical for visualizing blood vessels, arteries, and the heart chambers to diagnose cardiovascular conditions.
• Urography: Employed in intravenous pyelogram (IVP) studies to assess the structure and function of the kidneys, ureters, and bladder.
• Pharmaceutical Intermediates: Serves as a key chemical intermediate in the synthesis of other specialized contrast media or related diagnostic compounds.
• Research & Development: Utilized in biochemical and medical research for developing new imaging protocols and studying pharmacokinetics.

Basic Information

Product Name	Ioversol
CAS No.	87771-40-2
Molecular Formula	C24H36I3N3O9
Molecular Weight	807.28 g/mol
Synonyms	Ioversolum; 5-[N-(2-Hydroxyethyl)acetamido]-2,4,6-triiodo-N,N'-bis(2,3-dihydroxypropyl)isophthalamide; Optiray; Ioversolum; SQ-32692; Ioversol (USP); Ioversol API; 2,4,6-Triiodo-5-[(2-hydroxyethyl)amino]carbonyl]-N,N'-bis(2,3-dihydroxypropyl)isophthalamide
EINECS	Contact for details

Quality Control

Our Ioversol is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Each batch undergoes rigorous analytical testing to ensure identity, purity, potency, and safety. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters including assay, related substances, residual solvents, heavy metals, and microbiological limits. We are committed to supplying material that meets the stringent requirements of pharmaceutical GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5%; Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
pH (in solution)	6.5 - 7.5
Bacterial Endotoxins	< 1.0 EU/mg
Microbial Enumeration	Complies with Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.