Description

2,2,2-Trifluoro-1-(4-Methylphenyl)-o-[(4-Methylphenyl)Sulfonyl]Oxime Ethanone is a specialized fluorinated organic intermediate featuring a unique oxime sulfonate structure. This compound is valued for its role as a key building block in advanced synthetic chemistry, enabling the introduction of trifluoromethyl and sulfonyl functionalities. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique surface properties and chemical resistance.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions and nucleophilic substitution reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: Acts as a standard or reagent in academic and industrial research focused on the reactivity of fluorinated sulfonyl oximes.

Basic Information

Product Name	2,2,2-Trifluoro-1-(4-Methylphenyl)-o-[(4-Methylphenyl)Sulfonyl]Oxime Ethanone
CAS No.	87736-79-6
Molecular Formula	C16H14F3NO3S
Molecular Weight	357.35 g/mol
Synonyms	α-(Trifluoroacetyl)-p-methylbenzenesulfonamide O-(p-tolyl) oxime; 2,2,2-Trifluoro-1-(4-methylphenyl)ethanone O-[(4-methylphenyl)sulfonyl]oxime; p-Tolyl 2,2,2-trifluoro-1-(p-tolyl)ethan-1-one O-sulfonyloxime; 1-(4-Methylphenyl)-2,2,2-trifluoroethanone O-[(4-methylphenyl)sulfonyl]oxime; Trifluoroacetophenone p-toluenesulfonyl oxime; TFAP-TsOx; CAS 87736-79-6
EINECS	Contact for details

Quality Control

Our production of 2,2,2-Trifluoro-1-(4-Methylphenyl)-o-[(4-Methylphenyl)Sulfonyl]Oxime Ethanone adheres to a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures reliable performance in your sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider using an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.