Description

Boc-L-Leucine N,o-Dimethylhydroxamide is a protected amino acid derivative, specifically a leucine hydroxamate, that serves as a crucial building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the preparation of peptide mimetics, protease inhibitors, and other biologically active compounds. This high-purity reagent is essential for research and development laboratories in the pharmaceutical, biotechnology, and agrochemical sectors, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly protease inhibitors and enzyme modulators.
• Peptidomimetic Synthesis: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides, enhancing metabolic stability.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new therapeutic targets and optimize lead compounds.
• Bioconjugation & Probe Development: Serves as a specialized linker or handle for creating labeled molecules used in biochemical assays and diagnostic tools.
• Agrochemical Research: Utilized in the development of novel pesticides and herbicides that target specific enzymatic pathways.

Basic Information

Product Name	Boc-L-Leucine N,o-Dimethylhydroxamide
CAS No.	87694-52-8
Molecular Formula	C₁₃H₂₆N₂O₄
Molecular Weight	274.36 g/mol
Synonyms	Boc-Leu-N(Me)-ONMe2; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-methylpentanoic acid N,o-dimethylhydroxamide; N-(tert-Butoxycarbonyl)-L-leucine N,o-dimethylhydroxamate; tert-Butyl (S)-(1-(dimethylamino)-4-methyl-1-oxopentan-2-yl)carbamate; Boc-L-Leucine dimethylhydroxamic acid; L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-, N,o-dimethylhydroxamate
EINECS	Contact for details

Quality Control

Our Boc-L-Leucine N,o-Dimethylhydroxamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates to support our clients' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.