Description

Boc-Ala-N(Och3)Ch3 is a protected amino acid derivative, specifically an N-methylated and O-methylated alanine with a tert-butoxycarbonyl (Boc) protecting group. This compound is a crucial building block in modern peptide synthesis, offering enhanced stability and control during complex coupling reactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of N-methylated alanine residues, which can improve peptide metabolic stability and membrane permeability.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptide sequences where specific backbone modifications are required.
• Pharmaceutical Research: Serves as a critical reagent in the discovery and development of peptide-based drugs, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Enables the creation of modified peptide structures with tailored biological activity and improved pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for studying peptide structure-activity relationships and synthetic methodology.
• Bioconjugation: Can be used to introduce modified amino acid units into larger biomolecules for labeling or functionalization.

Basic Information

Product Name	Boc-Ala-N(Och3)Ch3
CAS No.	87694-49-3
Molecular Formula	C11H21NO5
Molecular Weight	247.29 g/mol
Synonyms	Boc-N-Me-Ala-OMe; (2S)-2-[(tert-Butoxycarbonyl)(methyl)amino]propanoic acid methyl ester; N-(tert-Butoxycarbonyl)-N-methyl-L-alanine methyl ester; Methyl N-(tert-butoxycarbonyl)-N-methylalaninate; Boc-N-methyl-L-alanine methyl ester; Boc-N-Me-Ala-OMe; N-Boc-N-methyl-L-alanine methyl ester
EINECS	Contact for details

Quality Control

Our Boc-Ala-N(Och3)Ch3 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.