Description

Ac-Dl-Phe(4-F)-Ome is a fluorinated, N-acetylated derivative of phenylalanine methyl ester, serving as a key chiral building block and intermediate in advanced organic synthesis. This compound is valued for its role in introducing the 4-fluorophenylalanine moiety, which is critical for modulating the biological activity, metabolic stability, and binding affinity of peptide-based pharmaceuticals. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, protease inhibitors, and other bioactive molecules where structural fine-tuning is essential.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated peptide analogs and potential active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the design and development of inhibitors targeting specific enzymes like HIV protease or renin.
• Peptidomimetics: Incorporation into non-natural peptide structures to enhance stability against enzymatic degradation and improve pharmacokinetic properties.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in studying protein-protein interactions and enzyme mechanisms.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique surface properties.
• Academic & Industrial R&D: A versatile reagent for method development in asymmetric synthesis and fluorine chemistry.

Basic Information

Product Name	Ac-Dl-Phe(4-F)-Ome
CAS No.	87586-97-8
Molecular Formula	C12H14FNO3
Molecular Weight	239.24 g/mol
Synonyms	N-Acetyl-4-fluoro-DL-phenylalanine methyl ester; Methyl N-acetyl-4-fluoro-DL-phenylalaninate; Ac-4-F-DL-Phe-OMe; N-Acetyl-4-fluorophenylalanine methyl ester; DL-4-Fluoro-N-acetylphenylalanine methyl ester; (RS)-N-Acetyl-4-fluorophenylalanine methyl ester; N-Acetyl-4-fluoro-DL-phenylalanine methyl ester; Methyl 2-acetamido-3-(4-fluorophenyl)propanoate
EINECS	Contact for details

Quality Control

Our Ac-Dl-Phe(4-F)-Ome is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.