Description

Calmodulin (20-31) is a specific, high-purity peptide fragment derived from the calmodulin protein, with the CAS registry number 87548-66-1. This compound is a critical research tool for studying calcium-mediated signal transduction pathways and protein-protein interactions. It is primarily utilized by biochemists, molecular biologists, and pharmaceutical researchers in academic institutions, R&D laboratories, and biotechnology companies for mechanistic studies and assay development.

Application

• Biochemical Research: As a specific substrate or inhibitor in enzymatic assays to study calmodulin-dependent processes.
• Signal Transduction Studies: Investigating the role of calcium/calmodulin in cellular signaling cascades.
• Protein-Protein Interaction Analysis: Used in binding studies (e.g., SPR, ITC) to map interaction domains with target enzymes like kinases and phosphatases.
• Pharmaceutical R&D: Screening and validation of novel drug candidates targeting calmodulin-mediated pathways.
• Antibody Production: Serving as an antigen for generating sequence-specific antibodies.
• Diagnostic Development: Potential use in developing assays for research into calcium-related disorders.

Basic Information

Item	Detail
Product Name	Calmodulin (20-31)
CAS No.	87548-66-1
Molecular Formula	C62H101N19O19
Molecular Weight	1384.6 g/mol
Synonyms	Calmodulin Fragment 20-31; CaM (20-31); Calmodulin-Derived Peptide (20-31); L-K-L-K-G-V-V-D-R-V-N-A-F-K; H-Lys-Leu-Lys-Gly-Val-Val-Asp-Arg-Val-Asn-Ala-Phe-Lys-OH; Calmodulin Binding Domain Peptide (20-31); CaMBP (20-31)
EINECS	Contact for details

Quality Control

Our Calmodulin (20-31) is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical characterization, including HPLC for purity verification and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive). For long-term storage, desiccate at -20°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Composition	Conforms to theoretical values (±10%)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.