Description

Streptolysin S From Streptococcus*Pyogenes is a potent, oxygen-stable hemolytic exotoxin produced by specific strains of *Streptococcus pyogenes*. This product is critical for research into bacterial pathogenesis, host immune response, and the development of diagnostic tools. It is primarily utilized by researchers and developers in the fields of microbiology, immunology, and pharmaceutical discovery.

Application

• Microbiological Research: Used as a key reagent to study the virulence mechanisms of *Streptococcus pyogenes* and its role in diseases like pharyngitis, scarlet fever, and necrotizing fasciitis.
• Immunological Studies: Employed to investigate host cell lysis, pore-formation in cell membranes, and the modulation of immune cell function.
• Diagnostic Development: Serves as a component in the development and validation of assays for detecting specific streptococcal infections or antibodies.
• Toxin-Antitoxin Research: Essential for studying neutralization mechanisms and evaluating potential therapeutic agents or vaccines targeting streptococcal toxins.
• Cell Biology: Utilized as a tool for controlled cell membrane permeabilization in various experimental protocols.
• Pharmaceutical Screening: Acts as a target compound in high-throughput screens for novel anti-virulence drugs or inhibitors.

Basic Information

Product Name	Streptolysin S From Streptococcus*Pyogenes
CAS No.	87502-32-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Streptolysin S; SLS; Streptococcal hemolysin S; Oxygen-stable streptolysin; Group A streptococcal exotoxin S; Pyrogenic exotoxin S; Hemolytic toxin S; Streptococcus pyogenes toxin S
EINECS	Contact for details

Quality Control

Our Streptolysin S is produced and handled under stringent conditions to ensure high biological activity and purity for research applications. Each batch undergoes comprehensive analytical testing, including activity assays and purity assessments. A Certificate of Analysis (COA) detailing specific batch results is provided to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically -20°C or as specified per batch) to maintain stability. This material is hygroscopic (moisture-sensitive); ensure containers are sealed properly after use to prevent degradation.

Specification

Item	Specification
Appearance	Lyophilized powder or solution (as specified)
Identification (Bioassay/IR)	Complies
Biological Activity (Hemolytic Units)	≥ [Value] U/mg
Purity (HPLC/SDS-PAGE)	≥ 95%
Protein Content	By Bradford or BCA assay
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Specified buffer
Sterility (for specific grades)	Sterile filtered

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.