Description

Substance P (3-11), α-Biotinyl-Lys(3)- CAS NO 87468-57-3 is a biotinylated peptide fragment derived from the neuropeptide Substance P, specifically targeting the C-terminal region. This modification is critical for enhancing detection and binding affinity in advanced biochemical research applications. It is primarily utilized by researchers and developers in the fields of neuroscience, molecular biology, and pharmaceutical discovery who require high-purity, well-characterized bioactive peptides for assay development and target validation.

Application

• Biochemical Research: A key reagent for studying Substance P receptor (NK1) interactions, signaling pathways, and neuroinflammatory processes.
• Assay Development: Used in the development and validation of ELISA, Western blot, and other immunoassays due to its biotin tag for streptavidin-based detection.
• Drug Discovery: Serves as a tool compound for screening and characterizing potential neurokinin receptor antagonists in pharmaceutical R&D.
• Neuroscience Studies: Applied in experimental models to investigate the role of Substance P in pain transmission, mood disorders, and gastrointestinal motility.
• Affinity Purification: Utilized in pull-down assays and affinity chromatography to isolate and study receptor proteins or binding partners.
• Diagnostic Probe Development: Acts as a component in the design of sensitive diagnostic probes for research into neurological conditions.

Basic Information

Product Name	Substance P (3-11), α-Biotinyl-Lys(3)- CAS NO 87468-57-3
CAS No.	87468-57-3
Molecular Formula	C71H112N20O18S
Molecular Weight	1541.8 g/mol
Synonyms	Biotinyl-Substance P (3-11); Biotin-Substance P (3-11); α-Biotinyl-Lys3-Substance P (3-11); Arg-Pro-Lys(Biotinyl)-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2; Biotinylated Substance P fragment 3-11; Neurokinin P fragment (3-11), Biotinylated; SP (3-11), Biotin-Lys3-
EINECS	Contact for details

Quality Control

This product is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. Our quality systems are designed to meet the rigorous standards expected in pharmaceutical and life science research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO, acetic acid solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.