Description

Fluoromethoxybenzene is a versatile aromatic ether building block characterized by the presence of both fluorine and methoxy substituents on the benzene ring. This unique molecular structure imparts valuable electronic and steric properties, making it a critical intermediate in advanced organic synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in molecules requiring fluorinated aromatic motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing organic electronic materials, contributing to the tuning of dielectric anisotropy and emission properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protected or functionalized aromatic starting material in medicinal chemistry research.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing novel aromatic compounds with specific olfactory characteristics.

Basic Information

Product Name	Fluoromethoxybenzene
CAS No.	87453-27-8
Molecular Formula	C7H7FO
Molecular Weight	126.13 g/mol
Synonyms	1-Fluoro-4-methoxybenzene; 4-Fluoroanisole; p-Fluoroanisole; 4-Fluoromethoxybenzene; p-Fluoromethoxybenzene; 1-Methoxy-4-fluorobenzene; Anisole, 4-fluoro-; FMOB
EINECS	Contact for details

Quality Control

Our Fluoromethoxybenzene is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.485 - 1.495
Density	1.10 - 1.15 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.