Description

4-[3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile is a high-value, multi-functional heterocyclic building block characterized by its pyrrole core and trifluoromethylphenyl substituent. This compound is essential for advanced research and development, particularly in the synthesis of novel, complex molecules where its unique structure imparts specific electronic and steric properties. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated system.
• Ligand and Catalyst Development: Employed in organometallic chemistry to develop specialized ligands for catalytic processes.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) in fluorine-containing molecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-[3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile
CAS No.	87388-15-6
Molecular Formula	C12H7F3N2
Molecular Weight	236.20 g/mol
Synonyms	3-Cyano-4-[3-(trifluoromethyl)phenyl]-1H-pyrrole; 1H-Pyrrole-3-carbonitrile, 4-[3-(trifluoromethyl)phenyl]-; 4-(3-Trifluoromethylphenyl)-1H-pyrrole-3-carbonitrile; 4-(α,α,α-Trifluoro-m-tolyl)-1H-pyrrole-3-carbonitrile; 3-Cyano-4-(3-trifluoromethylphenyl)pyrrole; 4-(3-(Trifluoromethyl)phenyl)-1H-pyrrole-3-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 4-[3-(Trifluoromethyl)Phenyl]-1H-Pyrrole-3-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.