Description

Cefpodoxime Proxetil CAS NO 87239-81-4 is an advanced third-generation cephalosporin antibiotic prodrug, designed for enhanced oral bioavailability and broad-spectrum activity. This compound is critically important for the development and formulation of effective antibacterial medications targeting a wide range of gram-positive and gram-negative pathogens. It is primarily needed by pharmaceutical manufacturers and research institutions engaged in producing and developing oral antibiotic therapies, veterinary medicines, and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical API Synthesis: Primary raw material for the manufacture of finished oral antibiotic dosage forms (tablets, suspensions).
• Human Antibacterial Therapy: Used in medications to treat respiratory tract infections, urinary tract infections, skin and soft tissue infections, and otitis media.
• Veterinary Pharmaceutical Applications: Formulated for treating bacterial infections in companion and livestock animals.
• Research & Development: Serves as a key reference standard and intermediate in microbiological and pharmacological research.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent generic versions of branded cefpodoxime proxetil drugs.
• Drug Delivery System Development: Investigated in novel formulation studies to improve stability and patient compliance.

Basic Information

Product Name	Cefpodoxime Proxetil
CAS No.	87239-81-4
Molecular Formula	C21H27N5O9S2
Molecular Weight	557.60 g/mol
Synonyms	Cefpodoxime Proxetil; (6R,7R)-7-[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetamido]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid 1-(isopropoxycarbonyloxy)ethyl ester; CS-807; U-76252; R-3763; Cefodox; Vantin (Brand Name); Cefpodoximum Proxetilum
EINECS	Contact for details

Quality Control

Our Cefpodoxime Proxetil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents, aligning with industry pharmacopeial guidelines. Compliance with relevant GMP principles is maintained throughout production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Optical Rotation	-85° to -95° (c=1, in methanol)
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Complies with Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.