Description

Boc-Dipropylglycine is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group and a dipropylglycine backbone. This compound is a critical building block in the synthesis of complex peptides and peptidomimetics, offering enhanced stability and controlled reactivity during solid-phase and solution-phase coupling reactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, medicinal chemistry, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Synthesis: Serves as a protected amino acid monomer for the controlled assembly of custom peptide sequences in both research and development settings.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to modify peptide properties such as metabolic stability, potency, and selectivity.
• Bioconjugation: Acts as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Incorporated into synthetic peptides used as probes to study enzyme function, protein-protein interactions, and cellular pathways.
• Process Development: Employed in the scale-up and optimization of synthetic routes for peptide therapeutics under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Boc-Dipropylglycine
CAS No.	87113-32-4
Molecular Formula	C₁₃H₂₅NO₄
Molecular Weight	259.34 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-2,2-dipropylglycine; (2,2-Dipropyl-2-((tert-butoxycarbonyl)amino)acetic acid; Boc-2,2-dipropylglycine; N-Boc-2,2-dipropylglycine; tert-Butyl (2,2-dipropyl-2-carboxyethyl)carbamate; 2-[(tert-Butoxycarbonyl)amino]-2,2-dipropylacetic acid; BOC-Dipropyl-Gly-OH
EINECS	Contact for details

Quality Control

Our Boc-Dipropylglycine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. A comprehensive Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.