Description

Prealbumin, Human is a high-purity plasma protein, also known as transthyretin, which serves as a critical transport protein for thyroxine and retinol-binding protein. Its consistent quality and high purity make it an essential reference standard and raw material for diagnostic and research applications. This product is primarily utilized by manufacturers in the in-vitro diagnostic (IVD) industry, biopharmaceutical research, and academic institutions focusing on metabolic and nutritional studies.

Application

• Clinical Diagnostic Assays: Used as a calibrator and control in immunoassays for the quantitative measurement of prealbumin (transthyretin) in human serum, a key marker for nutritional status and liver function.
• Biomedical Research: Serves as a critical reagent in studies of protein-protein interactions, amyloidosis (as transthyretin is an amyloidogenic protein), and thyroid hormone transport mechanisms.
• Reference Standard: Acts as a primary standard for the qualification and validation of analytical methods, including electrophoresis, chromatography, and mass spectrometry.
• Cell Culture & Bioprocessing: Employed as a component in specialized cell culture media and protein stabilization formulations.
• Therapeutic Development: Investigated in research for drug targeting and as a model protein in stability and formulation studies for biopharmaceuticals.

Basic Information

Product Name	Prealbumin, Human
CAS No.	87090-18-4
Molecular Formula	C H N O S (Contact for specific formula of isoform)
Molecular Weight	~55,000 Da (tetramer)
Synonyms	Transthyretin; TTR; Thyroxine-binding prealbumin; TBPA; Prealbumin 1 (PA1); ATTR; Human Prealbumin; Serum Prealbumin; PALB
EINECS	Contact for details

Quality Control

Our Prealbumin, Human is manufactured and tested under a rigorous quality management system. Each lot is characterized for identity, purity, and biological activity to ensure it meets the stringent requirements for diagnostic and research use. Certificates of Analysis (COA) detailing purity (by HPLC/SDS-PAGE), endotoxin levels, and functional activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant or storing at -20°C. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or solid
Identification (Immunological)	Conforms
Purity (SDS-PAGE)	≥ 95%
Purity (HPLC)	≥ 90%
Protein Content (Biuret)	≥ 90% of stated weight
Endotoxin	< 1.0 EU/mg
Biological Activity	Conforms to reference standard
Solubility	Soluble in water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.