Description

Ritanserin CAS NO 87051-43-2 is a selective serotonin receptor antagonist, primarily targeting the 5-HT2A and 5-HT2C subtypes. This compound is of significant interest in pharmaceutical research for its potential to modulate serotonergic pathways. It serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate for researchers and manufacturers developing novel therapeutics in neuroscience and psychiatry.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in API and finished drug product manufacturing.
• Neuroscience Research: A vital tool compound for in vitro and in vivo studies investigating serotonin receptor function, signal transduction, and behavioral pharmacology.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the synthesis and optimization of new central nervous system (CNS) active agents.
• Biochemical Assays: Employed in high-throughput screening (HTS) and receptor binding assays to identify and characterize new receptor ligands.
• Academic Research: Utilized in university and institutional labs for fundamental research on sleep, mood, cognition, and related neurological disorders.

Basic Information

Product Name	Ritanserin
CAS No.	87051-43-2
Molecular Formula	C28H31FN4O2
Molecular Weight	474.57 g/mol
Synonyms	Ritanserin; 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one; R 55667; R55667; (±)-Ritanserin
EINECS	Contact for details

Quality Control

Our Ritanserin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.