Description

(5-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile is a versatile and high-value heterocyclic nitrile building block, essential for advanced organic synthesis. Its core value lies in its bifunctional structure, incorporating both a reactive nitrile group and a substituted 1,2,4-triazole ring, enabling the construction of complex molecular architectures. This compound is critically needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the triazole moiety.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in coordination chemistry and homogeneous catalysis.
• Material Science Research: Employed in the creation of novel polymers, dyes, and photoactive materials where the triazole unit imparts specific electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile
CAS No.	86999-26-0
Molecular Formula	C5H6N4
Molecular Weight	122.13 g/mol
Synonyms	2-(5-Methyl-1H-1,2,4-triazol-3-yl)acetonitrile; (5-Methyl-1H-1,2,4-triazol-3-yl)acetonitrile; 3-Cyanomethyl-5-methyl-1,2,4-triazole; 5-Methyl-3-triazolylacetonitrile; Acetonitrile, (5-methyl-4H-1,2,4-triazol-3-yl)-; 86999-26-0; 5-Methyl-1H-1,2,4-triazole-3-acetonitrile
EINECS	Contact for details

Quality Control

Every batch of (5-Methyl-4H-1,2,4-Triazol-3-Yl)Acetonitrile is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for research and scale-up activities. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥95% to ≥98% by HPLC), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.