Description

(6R,7S)-7α-[[(S)-(2-Amino-4-Thiazolyl)[(3,4-Dihydroxybenzoyl)Amino]Acetyl]Amino]-8-Oxo-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the cephalosporin class of β-lactam antibiotics. This compound is a critical building block in the synthesis of next-generation, broad-spectrum antibiotics, offering a sophisticated chemical scaffold for targeted drug development. It is essential for pharmaceutical R&D laboratories and manufacturing facilities focused on developing and producing novel anti-infective agents to combat resistant bacterial strains.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: A key chiral intermediate in the production of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development: Used in medicinal chemistry for the design and synthesis of new antibacterial compounds with improved efficacy.
• Process Chemistry & Scale-Up: Serves as a critical starting material or intermediate in the optimization and commercial-scale manufacturing of antibiotic APIs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and regulatory testing of finished pharmaceutical products.
• Combinatorial Chemistry: Utilized in libraries for screening novel bioactive molecules against bacterial targets.

Basic Information

Item	Details
Product Name	(6R,7S)-7α-[[(S)-(2-Amino-4-Thiazolyl)[(3,4-Dihydroxybenzoyl)Amino]Acetyl]Amino]-8-Oxo-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
CAS No.	86833-76-3
Molecular Formula	C₂₁H₂₁N₅O₈S
Molecular Weight	503.49 g/mol
Synonyms	7β-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-[(3,4-dihydroxybenzoyl)amino]methyl-3-cephem-4-carboxylic Acid; Cephalosporin C-3' Side Chain Derivative; (6R,7S)-7-[[(2-Amino-4-thiazolyl)(3,4-dihydroxybenzoyl)glycyl]amino]-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; Advanced Cephalosporin Intermediate; 7-ACA Derivative; Antibiotic Intermediate 86833-76-3
EINECS	Contact for details

Quality Control

Our (6R,7S)-7α-[[(S)-(2-Amino-4-Thiazolyl)[(3,4-Dihydroxybenzoyl)Amino]Acetyl]Amino]-8-Oxo-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with stringent pharmaceutical-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and opened only under controlled conditions to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.