Description

Crf (Human, Rat) CAS NO 86784-80-7 is a high-purity synthetic peptide fragment corresponding to the corticotropin-releasing factor (CRF) sequence. This compound serves as a critical reference standard and research tool for neuroendocrine and stress response studies. It is essential for scientists and quality control laboratories in the pharmaceutical, biotechnology, and academic research sectors requiring precise biological reagents.

Application

• Biomedical Research: Used as a reference standard in studies investigating the hypothalamic-pituitary-adrenal (HPA) axis, stress physiology, and related neurological disorders.
• Assay Development & Validation: Critical for the calibration and quality control of immunoassays (ELISA, RIA) designed to detect and quantify CRF levels in biological samples.
• Pharmaceutical R&D: Employed in screening and characterizing potential drug candidates targeting CRF receptors for conditions like anxiety, depression, and metabolic diseases.
• Academic Studies: A key reagent for in vitro and in vivo experiments exploring the role of corticotropin-releasing factor in endocrine signaling pathways.
• Quality Control: Serves as a system suitability standard in analytical laboratories to ensure the performance and accuracy of chromatographic and spectroscopic methods.

Basic Information

Product Name	Crf (Human, Rat)
CAS No.	86784-80-7
Molecular Formula	C206H342N60O63S
Molecular Weight	4758.3 g/mol
Synonyms	Corticotropin-Releasing Factor (Human, Rat); CRF (1-41), human/rat; h/rCRF; Corticoliberin (human, rat); ACTH-Releasing Factor; CRH; Corticoliberin; Sauvagine-related peptide; CRF-41
EINECS	Contact for details

Quality Control

Our Crf (Human, Rat) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (Mass Spec)	Conforms
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.