Description

[[R,(-)]-1-Methyl-3-Butynyl]Benzene is a high-purity, chiral organic intermediate featuring a benzene ring substituted with a methyl-butynyl side chain. This compound matters as a versatile building block for synthesizing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Material Science: A building block for advanced polymers and liquid crystals with tailored optical or electronic properties.
• Academic & Industrial R&D: Employed in organic synthesis research to explore new reaction pathways and create complex molecular architectures.
• Flavor & Fragrance Chemistry: Potential intermediate for the synthesis of specific aromatic compounds.

Basic Information

Product Name	[[R,(-)]-1-Methyl-3-Butynyl]Benzene
CAS No.	86738-20-7
Molecular Formula	C11H12
Molecular Weight	144.21 g/mol
Synonyms	(R)-1-Methyl-3-butynylbenzene; (R)-1-Phenyl-3-methyl-1-butyne; (R)-α-Methyl-α-ethynylbenzeneethanol (tautomer); (R)-1-Methyl-1-phenyl-3-butyn-1-ol (tautomer); (R)-1-Phenyl-3-butyn-1-ol, 1-methyl-; (-)-1-Methyl-3-butynylbenzene; (R)-(-)-1-Methyl-3-butynylbenzene; Benzene, [(1R)-1-methyl-3-butyn-1-yl]-
EINECS	Contact for details

Quality Control

Our [[R,(-)]-1-Methyl-3-Butynyl]Benzene is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical integrity, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), enantiomeric excess (by chiral HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended to maintain product stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.