Description

Fasciculin CAS NO 86697-68-9 is a potent, naturally occurring polypeptide toxin that acts as a highly selective and irreversible inhibitor of acetylcholinesterase. This specific biochemical activity makes it an invaluable tool compound for neurological and pharmacological research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers studying cholinergic systems, enzyme kinetics, and neurodegenerative disease mechanisms.

Application

• Neuroscience Research: As a selective probe to study the structure and function of acetylcholinesterase in the central and peripheral nervous systems.
• Pharmacological Studies: Used in the development and validation of assays for screening potential acetylcholinesterase inhibitor drugs.
• Toxicology & Biochemistry: Employed as a reference standard in research investigating the mechanisms of neurotoxic agents and enzyme inhibition.
• Diagnostic Reagent Component: May be used in the formulation of specialized in-vitro diagnostic kits for research purposes.
• Academic & Institutional Research: A critical tool for fundamental studies on synaptic transmission, neuromuscular junctions, and related biochemical pathways.

Basic Information

Product Name	Fasciculin
CAS No.	86697-68-9
Molecular Formula	C184H282N56O55S7
Molecular Weight	Approx. 4370 g/mol
Synonyms	Fasciculin 1; Fasciculin-1; Toxin F7; Dendroaspis angusticeps toxin; Acetylcholinesterase inhibitor peptide; FAS; FASC; Mamba toxin fasciculin
EINECS	Contact for details

Quality Control

Our Fasciculin is produced and handled under stringent quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing including HPLC for purity assessment, mass spectrometry for identity confirmation, and biological activity assays to ensure consistent potency and specificity. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -70°C or below to prevent repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure containers are sealed under anhydrous conditions.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Biological Activity (AChE Inhibition)	≥ 98% of stated activity
Endotoxin Level	< 1.0 EU/µg
Water Content (Karl Fischer)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.