Description

3-Chlorotetrafluoropropanoic Acid Methyl Ester is a specialized fluorinated organic ester, a key intermediate in advanced chemical synthesis. This compound is valued for its unique combination of a reactive chlorotetrafluoropropanoyl moiety and a methyl ester group, enabling precise molecular modifications. It is primarily sought by research and development teams and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules requiring fluorinated building blocks.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those incorporating fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Liquid Crystal & Electronic Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals and dielectric materials for display technologies and electronic applications.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, imparting valuable properties such as oil/water repellency, chemical resistance, and low surface energy.
• Organic Synthesis Reagent: Acts as a versatile reagent in organic chemistry for introducing the chlorotetrafluoropropanoyl group into target molecules under controlled conditions.
• Surface Treatment Agent: Used in the formulation of specialty coatings and surface treatments that require durable, low-energy surfaces.

Basic Information

Product Name	3-Chlorotetrafluoropropanoic Acid Methyl Ester
CAS No.	86676-74-6
Molecular Formula	C4H3ClF4O2
Molecular Weight	194.51 g/mol
Synonyms	Methyl 3-Chlorotetrafluoropropanoate; 3-Chloro-2,2,3,3-tetrafluoropropanoic Acid Methyl Ester; Methyl 3-Chloro-2,2,3,3-tetrafluoropropionate; 3-Chlorotetrafluoropropionic Acid Methyl Ester; CF3CClFCOOCH3; Propanoic acid, 3-chloro-2,2,3,3-tetrafluoro-, methyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-Chlorotetrafluoropropanoic Acid Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to support your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong bases, strong oxidizing agents, and strong acids. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.