Description

n-tert-Butylpiperidine-4-Carboxamide is a high-purity, synthetically versatile piperidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique sterically hindered tert-butyl group attached to the piperidine nitrogen, which is instrumental in modulating the physicochemical and pharmacological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular interactions.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the tert-butylpiperidine moiety can contribute to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor or a functional component in the design of novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the synthesis of molecular probes to study biological pathways and protein functions due to its ability to introduce steric bulk.
• Material Science Research: Potential building block for specialty polymers and advanced organic materials requiring specific steric and electronic characteristics.

Basic Information

Product Name	n-tert-Butylpiperidine-4-Carboxamide
CAS No.	86542-86-1
Molecular Formula	C10H20N2O
Molecular Weight	184.28 g/mol
Synonyms	4-Carbamoyl-1-tert-butylpiperidine; 1-(1,1-Dimethylethyl)-4-piperidinecarboxamide; N-(tert-Butyl)isonipecotamide; tert-Butyl 4-carbamoylpiperidine-1-carboxylate (related precursor); 1-tert-Butylpiperidine-4-carboxylic acid amide; 4-Piperidinecarboxamide, 1-(1,1-dimethylethyl)-; N-tert-Butyl-4-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our n-tert-Butylpiperidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.