Description

2-Chloro-11-(4-(2-Hydroxybutyl)Piperazino)-10,11-Dihydrodibenzo(B,F)Th Iepin Methanesulfonate is a high-purity pharmaceutical intermediate and active ingredient of significant commercial interest. This compound matters for its critical role in the synthesis and development of advanced therapeutic agents, particularly in the central nervous system (CNS) sector. It is primarily needed by pharmaceutical R&D laboratories, API (Active Pharmaceutical Ingredient) manufacturers, and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel psychotropic and neuroactive pharmaceutical compounds.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for research into new therapeutic entities targeting CNS disorders.
• Biochemical Research: Used in academic and industrial research to study receptor interactions and pharmacological pathways.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Preclinical Studies: Utilized in the development and testing phases of new drug candidates before clinical trials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Chloro-11-(4-(2-Hydroxybutyl)Piperazino)-10,11-Dihydrodibenzo(B,F)Th Iepin Methanesulfonate
CAS No.	86499-09-4
Molecular Formula	C23H30ClN3O4S
Molecular Weight	480.02 g/mol
Synonyms	2-Chloro-11-[4-(2-hydroxybutyl)piperazin-1-yl]dibenzo[b,f][1,4]thiazepine methanesulfonate; Zotepine methanesulfonate; Zotepine mesylate; Lodopin (mesylate salt); Nipolept (mesylate salt); FR-1314 (mesylate); 10,11-Dihydro-2-chloro-11-[4-(2-hydroxybutyl)-1-piperazinyl]dibenzo[b,f]thiepin methanesulfonate
EINECS	Contact for details

Quality Control

Our 2-Chloro-11-(4-(2-Hydroxybutyl)Piperazino)-10,11-Dihydrodibenzo(B,F)Th Iepin Methanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.