Description

Cefodizime Sodium is a third-generation cephalosporin antibiotic in its sodium salt form, offering enhanced stability and solubility for pharmaceutical formulation. This compound is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it a critical active pharmaceutical ingredient (API). It is primarily required by pharmaceutical manufacturers and research institutions for the development and production of injectable antibiotic formulations.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable antibiotic formulations.
• Clinical Research: Utilized in preclinical and clinical studies for evaluating efficacy against resistant bacterial strains.
• Veterinary Medicine: Applied in the development of antibacterial treatments for livestock and companion animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control laboratories.
• Combinatorial Therapy: Investigated in combination with other agents for synergistic antimicrobial effects.

Basic Information

Product Name	Cefodizime Sodium
CAS No.	86329-79-5
Molecular Formula	C20H20N6O7S4•Na
Molecular Weight	628.66 g/mol
Synonyms	Cefodizime Sodium Salt; (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[(5-carboxy-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate Sodium; HR-221; THR-221; Cefodizim Sodium; Antibiotic HR 221; Cefodizime Na
EINECS	Contact for details

Quality Control

Our Cefodizime Sodium is manufactured under strict quality systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with common pharmacopeial requirements for cephalosporin APIs. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	5.5 - 7.5
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.