Description

Deoxy-Bigchap CAS NO 86303-23-3 is a high-purity, non-ionic detergent and surfactant widely used in biochemical research and pharmaceutical development. Its primary value lies in its ability to effectively solubilize membrane proteins while maintaining their native structure and function, which is critical for downstream analysis. This makes it an essential reagent for researchers and manufacturers in the life sciences, biotechnology, and pharmaceutical industries working on protein purification, structural biology, and diagnostic assay development.

Application

• Membrane Protein Solubilization: Extraction and stabilization of integral membrane proteins for functional and structural studies.
• Protein Purification: Used in chromatography buffers to maintain protein solubility and prevent aggregation during purification processes.
• Cell Lysis: Component of gentle lysis buffers for isolating intracellular organelles and protein complexes without denaturation.
• Diagnostic Assays: Employed as a stabilizing agent in immunoassay and diagnostic kit formulations to ensure reagent consistency.
• Crystallography: Aids in the crystallization of membrane proteins by creating stable protein-detergent complexes.
• Biophysical Analysis: Essential for techniques like surface plasmon resonance (SPR) and analytical ultracentrifugation where protein monodispersity is required.

Basic Information

Product Name	Deoxy-Bigchap
CAS No.	86303-23-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Deoxy-BIGCHAP; N,N-Bis(3-D-gluconamidopropyl)deoxycholamide; Deoxy Big CHAP; BIGCHAP, Deoxy-; Deoxy-Big CHAP Detergent; 3α,12α-Dihydroxy-5β-cholan-24-oic Acid N,N-Bis(3-D-gluconamidopropyl)amide
EINECS	Contact for details

Quality Control

Our Deoxy-Bigchap is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including purity assay and critical impurity profiling, to ensure it meets the high standards required for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent absorption of atmospheric moisture, which can affect performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Critical Micelle Concentration (CMC)	Contact for details
Solubility	Clear, colorless solution in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.