Description

Benzonitrile, 4-(1-Aminoethyl)- is a versatile aromatic nitrile derivative featuring a chiral aminoethyl side chain. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecules with high stereochemical fidelity. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in neurologically active compounds and receptor modulators.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Preparation: Used in the development of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate for dyes, pigments, and advanced polymer additives requiring specific optical or electronic properties.
• Academic and R&D: Valuable reagent in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	Benzonitrile, 4-(1-Aminoethyl)-
CAS No.	86225-78-7
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	4-(1-Aminoethyl)benzonitrile; 1-(4-Cyanophenyl)ethylamine; α-Methyl-4-cyanobenzylamine; p-(1-Aminoethyl)benzonitrile; 4-Cyanophenethylamine, α-methyl-; (RS)-1-(4-Cyanophenyl)ethanamine; 4-(Aminoethyl)benzonitrile; Benzenecarbonitrile, 4-(1-aminoethyl)-
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 4-(1-Aminoethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure consistency and meet the exacting standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee (Specific enantiomer available)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.