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(S)-(+)-4-Phenyl-2-Oxazolidinone CAS NO 86217-38-1


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CAS No.:86217-38-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(S)-(+)-4-Phenyl-2-Oxazolidinone is a high-value, enantiomerically pure chiral auxiliary and building block. This compound is critically important for the asymmetric synthesis of pharmaceutical intermediates and fine chemicals, enabling the production of single-isomer products with high stereoselectivity. It is primarily needed by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and complex organic molecules.

Application

  • Chiral Auxiliary in Asymmetric Synthesis: Widely used to induce stereoselectivity in aldol, alkylation, and Diels-Alder reactions.
  • Pharmaceutical Intermediate: Key building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
  • Agrochemical Synthesis: Employed in the research and production of chiral pesticides and herbicides.
  • Catalyst and Ligand Preparation: Serves as a precursor for novel chiral catalysts and ligands used in homogeneous catalysis.
  • Academic and Industrial R&D: Essential reagent for methodological development in organic chemistry and process chemistry.
  • Fine Chemical Production: Used in the manufacture of specialty chemicals requiring specific stereochemistry.

Basic Information

Product Name (S)-(+)-4-Phenyl-2-Oxazolidinone
CAS No. 86217-38-1
Molecular Formula C9H9NO2
Molecular Weight 163.17 g/mol
Synonyms (S)-4-Phenyl-2-oxazolidinone; (S)-(+)-4-Phenyl-2-oxazolidinone; (S)-4-Phenyloxazolidin-2-one; (S)-(-)-4-Phenyl-2-oxazolidinone (common naming variation); Evans Auxiliary (S)-isomer; (S)-BOZ; (S)-Phenyloxazolidinone; (4S)-4-Phenyl-1,3-oxazolidin-2-one
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Quality Control

Our (S)-(+)-4-Phenyl-2-Oxazolidinone is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable, ensuring reliable supply and consistent quality for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Melting Point 88 - 92 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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