Description

Cerebrocystatin CAS NO 86102-30-9 is a synthetic peptide inhibitor of cysteine proteases, specifically cathepsins B, H, and L. This compound is a critical research tool for studying proteolytic enzyme activity and its role in various physiological and pathological processes. It is primarily utilized by researchers and developers in the fields of neuroscience, biochemistry, and pharmaceutical discovery.

Application

• Neuroscience Research: Investigation of the role of cathepsins in neurodegenerative diseases, neuroinflammation, and neuronal signaling pathways.
• Biochemical Assay Development: Used as a specific inhibitor in enzymatic assays to study the kinetics and function of cysteine cathepsins.
• Apoptosis & Cell Death Studies: Research into programmed cell death mechanisms where cathepsin activity is a key component.
• Cancer Research: Exploration of tumor invasion and metastasis, as cathepsins are involved in extracellular matrix degradation.
• Inflammatory Disease Models: Study of conditions like arthritis and atherosclerosis where cathepsin activity contributes to tissue remodeling.
• Drug Discovery Screening: Serves as a reference compound or positive control in high-throughput screens for novel protease inhibitors.

Basic Information

Item	Details
Product Name	Cerebrocystatin
CAS No.	86102-30-9
Molecular Formula	C34H59N11O10S2
Molecular Weight	838.03 g/mol
Synonyms	Z-Phe-Tyr(O-Bzl)-CHN2; Benzyloxycarbonyl-Phe-Tyr(O-benzyl)-diazomethane; Z-Phe-Tyr(Bzl)-CHN2; Cathepsin B Inhibitor II; Cbz-Phe-Tyr(Bzl)-CHN2; Z-F-Y(Bzl)-CHN2; (Benzyloxycarbonyl)-Phe-Tyr(O-benzyl)-diazomethane
EINECS	Contact for details

Quality Control

Our Cerebrocystatin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and NMR for structural verification. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.