Description

2-(Trifluoromethyl)Thiophene is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique electronic properties imparted by the trifluoromethyl group, which is critical for modifying the physicochemical characteristics of target molecules. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and semiconductor applications.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis, leveraging the electron-withdrawing nature of the CF3 group.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial R&D focused on introducing fluorinated motifs into complex molecular architectures.
• Liquid Crystal and Display Technology: Used in the synthesis of fluorinated components for liquid crystal mixtures, improving display performance.

Basic Information

Product Name	2-(Trifluoromethyl)Thiophene
CAS No.	86093-76-7
Molecular Formula	C5H3F3S
Molecular Weight	152.14 g/mol
Synonyms	2-(Trifluoromethyl)thiophene; α,α,α-Trifluoro-2-thiophenemethane; 2-Thienyltrifluoromethane; 2-Trifluoromethylthiophene; Thiophene, 2-(trifluoromethyl)-; 2-CF3-Thiophene; 2-Thienyl trifluoromethyl ketone (reduction product); 2-(Trifluoromethyl)-1-thia-2,4-cyclopentadiene
EINECS	Contact for details

Quality Control

Our 2-(Trifluoromethyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, impurity profiles, and physical properties.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and fluorides. Recommended storage temperature is 2-8°C for long-term stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index	1.450 - 1.460
Density	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.