Description

Permethrin Impurity 7 (Permethrin EP Impurity G) is a defined chemical reference standard used for analytical and quality control purposes. This compound is critical for ensuring the purity, safety, and regulatory compliance of the active pharmaceutical ingredient (API) Permethrin and its formulations. It is primarily required by analytical laboratories, quality assurance departments, and manufacturers within the pharmaceutical and agrochemical industries for method development, validation, and routine batch testing.

Application

• Pharmaceutical Reference Standard: Used as a certified impurity standard for the identification and quantification of Permethrin EP Impurity G in Permethrin API and finished drug products, ensuring compliance with pharmacopoeial monographs (e.g., European Pharmacopoeia, USP).
• Analytical Method Development & Validation: Essential for developing, optimizing, and validating chromatographic methods (HPLC, GC) to accurately separate and measure this specific impurity.
• Quality Control & Batch Release: A critical component in the QC testing of Permethrin raw materials and formulations to confirm they meet stringent impurity profile specifications.
• Stability Studies: Employed to monitor the formation and levels of this impurity over time in stability testing of Permethrin-based products.
• Regulatory Submissions: Supports regulatory filings (e.g., for FDA, EMA) by providing a characterized impurity for method descriptions and specification justifications.
• Research & Development: Used in R&D to study the degradation pathways and impurity formation mechanisms of Permethrin.

Basic Information

Product Name	Permethrin Impurity 7 (Permethrin EP Impurity G)
CAS No.	85576-82-5
Molecular Formula	C21H20Cl2O3
Molecular Weight	391.29 g/mol
Synonyms	Permethrin Impurity G; Permethrin Related Compound G; 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid (3-Phenoxyphenyl)methyl Ester (Isomer); (1R,3R)- and (1S,3S)-Isomers of Permethrin; Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (3-phenoxyphenyl)methyl ester, (1R,3R)-rel-; Permethrin cis/trans Isomer Mixture (Impurity); Permethrin EP Impurity G
EINECS	Contact for details

Quality Control

Our Permethrin Impurity 7 is manufactured and handled under strict quality systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for use as a reference material. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing the purity, analytical methods, and batch-specific data.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference spectrum
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual unknown impurity: ≤ 0.5% Total impurities: ≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.