Description

n-Trifluoroacetyl-3,4-(Methylene-Dioxy)-Aniline is a specialized aromatic amine derivative featuring a trifluoroacetyl protecting group and a methylenedioxy functional motif. This compound is a critical high-purity intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. It is primarily required by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its unique fluorine-containing scaffold.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing the trifluoroacetyl-protected aniline moiety into target molecules in medicinal chemistry.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and developing novel fluorinated compounds.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced materials requiring specific aromatic amine components.

Basic Information

Product Name	n-Trifluoroacetyl-3,4-(Methylene-Dioxy)-Aniline
CAS No.	85575-56-0
Molecular Formula	C10H6F3NO3
Molecular Weight	245.16 g/mol
Synonyms	1-(3,4-Methylenedioxyphenyl)-2,2,2-trifluoroethan-1-imine; 3,4-(Methylenedioxy)aniline, N-trifluoroacetyl-; N-(3,4-Methylenedioxyphenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(1,3-benzodioxol-5-yl)acetamide; 5-(Trifluoroacetylamino)-1,3-benzodioxole; Piperonylamine, N-trifluoroacetyl-; TFA-protected 3,4-methylenedioxyaniline
EINECS	Contact for details

Quality Control

Our n-Trifluoroacetyl-3,4-(Methylene-Dioxy)-Aniline is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.