Description

1-Cyclopentene-1-Aceticacid,α-Amino-α-Methyl-(9Ci) is a specialized chiral amino acid derivative featuring a cyclopentene backbone, which is pivotal for constructing complex molecular architectures. This compound serves as a high-value pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for the development of novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Asymmetric Synthesis: Employed as a sophisticated building block for constructing complex, stereochemically defined molecules in medicinal chemistry and process R&D.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Peptidomimetics: Incorporated into peptide analogs to modulate biological activity, stability, and pharmacokinetic properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up novel synthetic routes.

Basic Information

Item	Detail
Product Name	1-Cyclopentene-1-Aceticacid,α-Amino-α-Methyl-(9Ci)
CAS No.	85564-12-1
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	α-Amino-α-methyl-1-cyclopentene-1-acetic acid; 1-Cyclopentene-1-acetic acid, α-amino-α-methyl-; (1-Cyclopenten-1-yl)-α-methylalanine; 2-Amino-2-methyl-4-cyclopentene-4-butanoic acid; 2-Amino-2-methyl-4-cyclopentylidene butanoic acid; Amino-methyl-cyclopentene acetic acid; Cyclopentene amino acid derivative
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this advanced intermediate. Production adheres to current Good Manufacturing Practice (cGMP) principles where applicable, ensuring batch-to-batch consistency and traceability. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA), documenting purity, enantiomeric excess, and impurity profiles, is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.