Description

Technetium Tc 99M n-Phosphorylaminoethyl Phosphate is a diagnostic radiopharmaceutical agent used in nuclear medicine imaging. This compound is critical for its role in skeletal scintigraphy, allowing for the visualization of bone metabolism and pathology. It is primarily needed by radiopharmacies, nuclear medicine departments, and clinical research organizations for the preparation of patient-specific doses.

Application

• Bone Scintigraphy (Bone Scan): The primary application for detecting bone metastases, fractures, infections (osteomyelitis), and evaluating prosthetic joints.
• Oncological Imaging: Staging and monitoring of cancers known to metastasize to bone, such as breast, prostate, and lung cancer.
• Orthopedic Evaluation: Assessment of unexplained bone pain, trauma, sports injuries, and complex regional pain syndrome.
• Infection Imaging: Localization of sites of bone and joint infections when combined with single-photon emission computed tomography (SPECT).
• Metabolic Bone Disease Assessment: Aiding in the evaluation of conditions like Paget's disease of bone.
• Radiopharmaceutical Kit Component: Used as the active pharmaceutical ingredient (API) in the preparation of sterile, pyrogen-free diagnostic kits.

Basic Information

Product Name	Technetium Tc 99M n-Phosphorylaminoethyl Phosphate
CAS No.	85561-27-9
Molecular Formula	C2H9NO6P2 • 99mTc
Molecular Weight	Contact for details
Synonyms	Technetium-99m n-Phosphorylaminoethyl Phosphate; Tc-99m n-Phosphorylaminoethyl Phosphate; 99mTc-n-Phosphorylaminoethyl Phosphate; n-Phosphorylaminoethyl Phosphate Tc 99m; Tc-99m PAEP; Bone Scan Agent; Diagnostic Radiopharmaceutical
EINECS	Contact for details

Quality Control

Manufactured under strict cGMP (current Good Manufacturing Practice) guidelines for radiopharmaceuticals. Each batch is tested to ensure compliance with pharmacopeial standards for radiochemical purity, radionuclidic purity, sterility, and apyrogenicity. Comprehensive Certificates of Analysis (COA) detailing all release specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature or as specified on the product label. Due to the radioactive nature of Technetium-99m, adhere to all local and international regulations for the storage, handling, and disposal of radioactive materials. Use appropriate shielding.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
pH	5.0 - 7.5
Radionuclidic Identity (Half-life)	6.0 hours
Radionuclidic Purity (99Mo)	≤ 0.1%
Radiochemical Purity (HPLC/TLC)	≥ 95.0%
Sterility Test	Sterile
Bacterial Endotoxins	< 175 EU/Vial
Aluminum Content	≤ 10 µg/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.