Description

Pyr-Glu-Pro-Nh2 CAS NO 85541-78-2 is a high-purity synthetic peptide derivative, specifically a pyroglutamyl-glutamyl-proline amide. This compound is valued for its role as a key intermediate and building block in advanced pharmaceutical research and peptide synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and conducting biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in proteomics research, enzyme-substrate studies, and metabolic pathway analysis.
• Peptide Library Construction: A valuable component for creating combinatorial peptide libraries used in drug discovery and screening.
• Cosmeceutical Development: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.
• Diagnostic Reagent Manufacturing: Employed in the production of specialized reagents for clinical diagnostics and assay kits.

Basic Information

Product Name	Pyr-Glu-Pro-Nh2
CAS No.	85541-78-2
Molecular Formula	C13H20N4O5
Molecular Weight	312.32 g/mol
Synonyms	Pyroglutamyl-glutamyl-proline amide; pGlu-Glu-Pro-NH2; L-Pyroglutamyl-L-glutamyl-L-prolinamide; 5-Oxo-L-prolyl-L-glutamyl-L-prolinamide; Pyr-Glu-Pro-NH2; pGlu-E-Pro-NH2; TRH Metabolite (partial sequence); (S)-2-((S)-5-Amino-1-((S)-2-aminopropanoyl)-5-oxopentan-2-yl)-5-oxopyrrolidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our Pyr-Glu-Pro-Nh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including research-grade and GMP-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions, ideally with desiccant. For long-term storage, consider storing at -20°C under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.