Description

Synenkephalin is a synthetic peptide fragment corresponding to the N-terminal region of proenkephalin A, a key precursor to endogenous opioid peptides. This compound is of significant value in biochemical and pharmacological research as a standard and tool for studying opioid peptide processing, receptor interactions, and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on neuroscience, pain management, and neuroendocrinology.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in analytical methods such as HPLC and mass spectrometry for quantifying enkephalin-related peptides.
• Pharmacological Studies: Serves as a critical tool for investigating the metabolism, enzymatic cleavage, and biological activity of proenkephalin-derived peptides.
• Antibody Production & Immunoassays: Acts as an antigen for generating specific antibodies used in ELISA, RIA, and immunohistochemistry applications.
• Neuroscience Research: Employed in studies exploring the role of endogenous opioid systems in pain modulation, stress response, and addictive behaviors.
• Cell Culture & In Vitro Assays: Used in experimental models to examine cellular responses and receptor binding characteristics.

Basic Information

Product Name	Synenkephalin
CAS No.	85497-46-7
Molecular Formula	C27H40N6O8
Molecular Weight	576.65 g/mol
Synonyms	Proenkephalin A (1-8); Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val; [Met5]-Enkephalin-Arg6-Gly7-Leu8; Peptide E (1-8); BAM-8P; Adrenorphin (1-8); ME-Arg-Gly-Leu; Syn-enkephalin
EINECS	Contact for details

Quality Control

Our Synenkephalin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Our commitment to quality assurance guarantees material integrity for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.