Description

Tris(2,6-Dimethoxyphenyl)Phosphine is a specialized organophosphorus ligand characterized by its sterically hindered, electron-rich structure. This compound is highly valued in catalysis for its ability to stabilize reactive metal centers and facilitate challenging cross-coupling reactions. It is an essential reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of complex organic molecules.

Application

• Homogeneous Catalysis: As a key ligand in palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura, Buchwald-Hartwig amination, and Negishi couplings.
• Pharmaceutical Intermediates: Enabling the synthesis of complex, high-value drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides requiring selective bond formation.
• Material Science: Facilitating the creation of organic electronic materials, polymers, and ligands for novel metal-organic frameworks (MOFs).
• Asymmetric Synthesis: Potential use in creating chiral catalysts for enantioselective transformations.
• Academic & Industrial R&D: A critical tool for method development and exploring new catalytic pathways in chemical research.

Basic Information

Product Name	Tris(2,6-Dimethoxyphenyl)Phosphine
CAS No.	85417-41-0
Molecular Formula	C24H27O6P
Molecular Weight	442.44 g/mol
Synonyms	Tris(2,6-dimethoxyphenyl)phosphane; Phosphorous tris(2,6-dimethoxyphenyl); 2,6-Dimethoxyphenylphosphine; Tris(o,o'-dimethoxyphenyl)phosphine; TDMPP; Ligand TDMPP; Tris(2,6-dimethoxy-phenyl)-phosphine
EINECS	Contact for details

Quality Control

Our production of Tris(2,6-Dimethoxyphenyl)Phosphine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, critical for sensitive catalytic applications. Each lot is analyzed using advanced techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This compound is easily oxidized and moisture-sensitive; prolonged exposure to air should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR	Conforms to structure
31P NMR	Conforms to structure
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.