Description

Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Phe(3)-Arg(6)-Alanh2(10)- CAS NO 85416-56-4 is a synthetic peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH), specifically designed with targeted amino acid substitutions to modulate biological activity. This compound is of significant value for advanced research in endocrinology and oncology, serving as a critical tool for studying hormone-dependent pathways. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on developing novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the development of novel LHRH-based therapeutics for hormone-sensitive conditions.
• Endocrinology Studies: For in vitro and in vivo research to investigate the structure-activity relationship (SAR) of LHRH analogs and their interaction with receptors.
• Oncology Research: Utilized in preclinical studies targeting hormone-dependent cancers, such as prostate and breast cancer, to evaluate efficacy and mechanisms of action.
• Biochemical Assay Development: Serves as a critical component in developing high-throughput screening (HTS) assays and diagnostic kits for hormonal disorders.
• Peptide Chemistry & Synthesis: Used as a building block or model compound for studying advanced peptide synthesis techniques and stability.

Basic Information

Product Name	Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Phe(3)-Arg(6)-Alanh2(10)- CAS NO 85416-56-4
CAS No.	85416-56-4
Molecular Formula	C64H83ClN18O12
Molecular Weight	1307.9 g/mol
Synonyms	LHRH Analog; [Ac-D-4-Cl-Phe1, D-Phe2, D-Arg6, Ala10]-LHRH; Luteinizing Hormone-Releasing Hormone (4-10) fragment analog; Gonadorelin analog; GnRH antagonist analog; pGlu-His-Trp-Ser-Tyr-D-4-Cl-Phe-D-Phe-Arg-Pro-Ala-NH2; CAS 85416-56-4
EINECS	Contact for details

Quality Control

Our Lhrh, n-Ac-(4-Cl-Phe)(1,2)-Phe(3)-Arg(6)-Alanh2(10)- CAS NO 85416-56-4 is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.