Description

2-[(3S)-3-Hydroxy-2-Oxo-Pyrrolidin-1-Yl]Acetamide is a high-purity chiral intermediate featuring a hydroxy pyrrolidone core structure. This compound is critical for ensuring the stereochemical integrity and bioactivity of advanced pharmaceutical compounds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of novel active pharmaceutical ingredients (APIs), particularly in the areas of neurological and metabolic therapies.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, especially those targeting the central nervous system.
• Nootropic & Cognitive Enhancer Research: Serves as a precursor in the development of compounds designed to improve memory and cognitive function.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) requiring specific (S)-configuration stereochemistry.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and proteomics research due to its specific interaction with biological targets.
• Fine Chemical Production: Acts as a versatile synthon for creating more complex, high-value specialty chemicals with defined stereocenters.

Basic Information

Product Name	2-[(3S)-3-Hydroxy-2-Oxo-Pyrrolidin-1-Yl]Acetamide
CAS No.	85348-46-5
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(S)-2-(3-Hydroxy-2-oxopyrrolidin-1-yl)acetamide; 1-Acetamidoacetyl-3-hydroxy-2-pyrrolidinone; (3S)-3-Hydroxy-1-(2-amino-2-oxoethyl)-2-pyrrolidinone; 2-[(3S)-3-Hydroxy-2-oxo-1-pyrrolidinyl]acetamide; N-Acetyl-3-hydroxy-2-pyrrolidinone; 85348-46-5; UNII-6T0I4P8Q6G
EINECS	Contact for details

Quality Control

Our 2-[(3S)-3-Hydroxy-2-Oxo-Pyrrolidin-1-Yl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.