Description

Trh-Gly CAS NO 85344-77-0 is a specialized peptide derivative, specifically a thyrotropin-releasing hormone (TRH) analog, valued for its high purity and consistent performance in advanced research and development. This compound is critical for biochemical studies involving neuroendocrine signaling and peptide hormone research. It serves as an essential building block and reference standard for pharmaceutical R&D, academic institutions, and biotechnology companies focused on neuroscience, endocrinology, and diagnostic applications.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the development of neuroendocrine therapeutics and diagnostic agents.
• Biochemical & Neuroendocrine Studies: Essential for in vitro and in vivo research on thyrotropin-releasing hormone (TRH) receptor interactions and signal transduction pathways.
• Peptide Synthesis: Serves as a protected peptide fragment or a model compound in solid-phase and solution-phase peptide synthesis.
• Academic & Institutional Research: A vital tool for universities and research institutes studying hypothalamic-pituitary-thyroid axis regulation.
• Diagnostic Development: Potential use in the development of immunoassays and other diagnostic tests related to thyroid function.
• Biotechnology Reagents: Incorporated into high-purity reagent kits for cellular and molecular biology applications.

Basic Information

Item	Details
Product Name	Trh-Gly
CAS No.	85344-77-0
Molecular Formula	C16H22N6O4
Molecular Weight	362.38 g/mol
Synonyms	TRH-Glycine; L-Pyroglutamyl-L-histidyl-L-prolinamide Glycine; (PyroGlu-His-Pro-NH2)-Gly; Thyroliberin Glycine Derivative; TRH Analog; pGlu-His-Pro-NH2-Gly; Thyrotropin-Releasing Hormone Glycine Conjugate
EINECS	Contact for details

Quality Control

Our Trh-Gly is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for research and development. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing specific test results is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.