Description

Desethylcarbamoyl Cabergoline is a key pharmaceutical intermediate and a major metabolite of the dopamine agonist cabergoline. This compound is critical for research and development in the pharmaceutical sector, particularly for studying drug metabolism and pharmacokinetics. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on developing and analyzing neurological and endocrine therapies.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis and research of cabergoline and related dopaminergic compounds.
• Metabolite Reference Standard: Used as a certified reference material (CRM) in bioanalytical studies for accurate quantification of cabergoline metabolites in biological samples.
• Pharmacology Research: Essential for in-vitro and in-vivo studies investigating the metabolic pathways, efficacy, and safety profile of cabergoline.
• Analytical Method Development: Serves as a high-purity standard for developing and validating HPLC, LC-MS, and other chromatographic assays in quality control laboratories.
• Impurity Profiling: Employed to identify, characterize, and control process-related impurities in cabergoline active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	Desethylcarbamoyl Cabergoline
CAS No.	85329-86-8
Molecular Formula	C24H33N3O2
Molecular Weight	395.54 g/mol
Synonyms	N-Desethylcarbamoyl Cabergoline; 1-[(6-Allylergolin-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea; Cabergoline Metabolite; FCE 21336; (8β)-N-[(3-Dimethylamino)propyl]-N-ethyl-6-(2-propen-1-yl)ergoline-8-carboxamide; 6-Allyl-8β-carboxy-N-ethyl-N-[3-(dimethylamino)propyl]ergoline-amide
EINECS	Contact for details

Quality Control

Our Desethylcarbamoyl Cabergoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis to ensure it meets exacting standards for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified purity criteria, typically ≥95% to ≥98%.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.