Description

Heme A3 Bis-Imidazole CAS NO 85201-86-1 is a specialized coordination complex of heme A3, a critical prosthetic group found in cytochrome c oxidase, with two imidazole ligands. This compound is of significant value for biochemical research and industrial catalysis due to its role in modeling the active site of terminal oxidases involved in cellular respiration. It is primarily needed by researchers in enzymology, bioinorganic chemistry, and by manufacturers developing biomimetic catalysts or diagnostic reagents.

Application

• Biochemical Research: As a model compound for studying the structure and function of cytochrome c oxidase and other heme-copper oxidases.
• Enzyme Mechanism Studies: Investigation of oxygen reduction, proton pumping, and electron transfer processes in respiratory chains.
• Bioinorganic Catalyst Development: Serving as a precursor or inspiration for designing synthetic catalysts for oxidation reactions and small molecule activation.
• Pharmaceutical Intermediates: Potential use in the synthesis of complex molecules targeting respiratory pathways or as spectroscopic probes.
• Diagnostic Reagents: Development of colorimetric or spectroscopic assays based on heme-protein interactions.
• Material Science: Incorporation into biosensors or hybrid materials that leverage its redox-active properties.

Basic Information

Product Name	Heme A3 Bis-Imidazole
CAS No.	85201-86-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Heme a3 Bisimidazole; Cytochrome a3 Heme Bis-Imidazole Complex; Ferroheme a3 Bisimidazole; Iron Protoporphyrin a3 Bis-imidazole Adduct; Heme A3-Imidazole Coordination Compound; Bis(imidazole)heme a3; Heme O Bis-imidazole (related); Heme-Copper Oxidase Model Compound
EINECS	Contact for details

Quality Control

Our Heme A3 Bis-Imidazole is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research applications. While specific pharmacopeial standards (USP, EP) may not be directly applicable, quality is assured through analytical techniques including HPLC, UV-Vis spectroscopy, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and relevant spectroscopic data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C or as indicated on the label or COA. This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). For long-term storage, consider keeping under an inert atmosphere such as argon or nitrogen at -20°C.

Specification

Item	Specification
Appearance	Dark brown to black solid
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.