Description

3,4-Difluorobenzamide is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluorobenzene moiety, which can significantly alter the physicochemical and metabolic properties of target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro substitution pattern can enhance biological activity and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in displays and lighting.
• Polymer Modification: Employed to incorporate fluorine into polymer backbones or side chains, aiming to increase chemical resistance, thermal stability, or alter surface properties.
• Chemical Research & Development: A versatile building block for academic and industrial research in organofluorine chemistry, facilitating structure-activity relationship (SAR) studies.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments that require specific light-fastness and color properties.

Basic Information

Product Name	3,4-Difluorobenzamide
CAS No.	85118-04-3
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	3,4-Difluorobenzamide; Benzamide, 3,4-difluoro-; 3,4-Difluorobenzoic acid amide; 85118-04-3; 3,4-DFBA; m,p-Difluorobenzamide; 3,4-Difluorobenzenecarboxamide
EINECS	Contact for details

Quality Control

Every batch of 3,4-Difluorobenzamide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) documenting identity, purity (typically ≥98% by HPLC), and impurity profiles is available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.